Mutational signature learning with supervised negative binomial non-negative matrix factorization

Topic supervised non-negative matrix factorization

Topic models have been extensively used to organize and interpret the contents of large, unstructured corpora of text documents. Although topic models often perform well on traditional training vs. test set evaluations, it is often the case that the results of a topic model do not align with human interpretation. This interpretability fallacy is largely due to the unsupervised nature of topic m...

Negative Binomial Matrix Factorization for Recommender Systems

We introduce negative binomial matrix factorization (NBMF), a matrix factorization technique specially designed for analyzing over-dispersed count data. It can be viewed as an extension of Poisson matrix factorization (PF) perturbed by a multiplicative term which models exposure. This term brings a degree of freedom for controlling the dispersion, making NBMF more robust to outliers. We show th...

Non-negative matrix factorization

Semi-Supervised Projective Non-Negative Matrix Factorization for Cancer Classification

Advances in DNA microarray technologies have made gene expression profiles a significant candidate in identifying different types of cancers. Traditional learning-based cancer identification methods utilize labeled samples to train a classifier, but they are inconvenient for practical application because labels are quite expensive in the clinical cancer research community. This paper proposes a...

Supervised non-negative matrix factorization for audio source separation

Source separation is a widely studied problems in signal processing. Despite the permanent progress reported in the literature it is still considered a significant challenge. This chapter first reviews the use of non-negative matrix factorization (NMF) algorithms for solving source separation problems, and proposes a new way for the supervised training in NMF. Matrix factorization methods have ...